India's Shubman Gill, Washington Sundar and Avesh Khan have been ruled out of the Test series against England because of injury.
All-rounder Sundar misses out with a finger injury, while fast bowler Khan fractured his thumb in a warm-up match.
Batsmen Prithvi Shaw and Suryakumar Yadav have been named as replacements.
The pair have been called up from India's second-string squad which is currently playing a Twenty20 series in Sri Lanka.
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Meanwhile, wicketkeeper Rishabh Pant has linked up with the squad in England after recovering from Covid-19, while bowling coach Bharat Arun and Wriddhiman Saha and Abhimanyu Easwaran have completed their period of isolation.
The first Test in the five-match series begins on 4 August at Trent Bridge in Nottingham.
India's squad: Rohit Sharma, Mayank Agarwal, Cheteshwar Pujara, Virat Kohli (captain), Ajinkya Rahane (vice-captain), Hanuma Vihari, Rishabh Pant (wicketkeeper), R Ashwin, Ravindra Jadeja, Axar Patel, Jasprit Bumrah, Ishant Sharma, Mohd. Shami, Md. Siraj, Shardul Thakur, Umesh Yadav, KL Rahul, Wriddhiman Saha (wicketkeeper), Abhimanyu Easwaran, Prithvi Shaw, Suryakumar Yadav.
Standby players: Prasidh Krishna, Arzan Nagwaswalla.